• Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Karavasiloglou, Nena; Hüsing, Anika; Masala, Giovanna; van Gils, Carla H.; Fortner, Renée Turzanski; Chang-Claude, Jenny; Huybrechts, Inge; Weiderpass, Elisabete; Gunter, Marc; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Tjønneland, Anne; Kyrø, Cecilie; Dahm, Christina C.; Vistisen, Helene Tilma; Bakker, Marije F.; Sánchez, María-José; Chirlaque López, María Dolores; Santiuste, Carmen; Ardanaz, Eva; Menéndez, Virginia; Agudo, Antonio; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Peppa, Eleni; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Butt, Salma Tunå; Borgquist, Signe; Skeie, Guri; Schulze, Matthias; Key, Timothy; Khaw, Kay-Tee; Tsilidis, Konstantinos K.; Ellingjord-Dale, Merete; Riboli, Elio; Kaaks, Rudolf; Dossus, Laure; Rohrmann, Sabine; Kühn, Tilman (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-02)
      <i>Background</i> - Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established risk factors for invasive breast cancer have a similar impact on BCIS risk, but large population-based studies on lifestyle factors and BCIS risk are lacking. Thus, ...
    • Alcohol consumption and risk of urothelial cell bladder cancer in the European prospective investigation into cancer and nutrition cohort 

      Botteri, Edoardo; Ferrari, Pietro; Roswall, Nina; Tjønneland, Anne; Hjartåker, Anette; Huerta, José María; Fortner, Renée Turzanski; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Pala, Valeria; Pérez-Cornago, Aurora; Sonestedt, Emily; Liedberg, Fredrik; Overvad, Kim; Sánchez, María-José; Gram, Inger Torhild; Stepien, Magdalena; Trijsburg, Laura; Ljungberg, Börje; Johansson, Mikael B.; Kühn, Tilman; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-31)
      Findings on the association between alcohol consumption and bladder cancer are inconsistent. We investigated that association in the European Prospective Investigation into Cancer and Nutrition cohort. We included 476,160 individuals mostly aged 35-70 years, enrolled in ten countries and followed for 13.9 years on average. Hazard ratios (HR) for developing urothelial cell carcinoma (UCC; 1,802 ...
    • Alcohol intake and breast cancer in the European prospective investigation into cancer and nutrition 

      Romieu, Isabelle; Scoccianti, Chiara; Chajès, Véronique; De Batlle, Jordi; Biessy, Carine; Dossus, Laure; Baglietto, Laura; Clavel-Chapelon, Françoise; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Lukanova, Annekatrin; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; van Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; García, José Ramón Quirós; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano, Pilar; Borgquist, Signe; Wirfält, Elisabet; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Ferrari, Pietro; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-09)
      Alcohol intake has been associated to breast cancer in pre and postmenopausal women; however results are inconclusive regarding tumor hormonal receptor status, and potential modifying factors like age at start drinking. Therefore, we investigated the relation between alcohol intake and the risk of breast cancer using prospective observational data from the European Prospective Investigation into ...
    • Association between soft drink consumption and mortality in 10 European countries 

      Mullee, Amy; Romaguera, Dora; Pearson-Stuttard, Jonathan; Viallon, Vivian; Stepien, Magdalena; Freisling, Heinz; Fagherazzi, Guy; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Kaaks, Rudolf; Boeing, Heiner; Aleksandrova, Krasimira; Tjønneland, Anne; Halkjær, Jytte; Overvad, Kim; Weiderpass, Elisabete; Skeie, Guri; Parr, Christine Louise; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Tong, Tammy Y.N.; Schmidt, Julie A.; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Verschuren, W.M. Monique; Boer, Jolanda M.A.; Vermeulen, Roel; Ramne, Stina; Sonestedt, Emily; Van Guelpen, Bethany; Holgersson, Pernilla Lif; Tsilidis, Konstantinos K.; Heath, Alicia K.; Muller, David; Riboli, Elio; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
      <i>Importance</i> - Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.<p><p> <i>Objective</i> - To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.<p><p> <i>Design, ...
    • Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort 

      Matejcic, Marco; De Batlle, Jordi; Ricci, Cristian; Biessy, Carine; Perrier, Flavie; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Cadeau, Claire; His, Mathilde; Cox, David G.; Boeing, Heiner; Fortner, Renée Turzanski; Kaaks, Rudolf; Lagiou, Pagona; Trichopoulou, Antonia; Benetou, Vassiliki; Tumino, Rosario; Panico, Salvatore; Sieri, Sabina; Palli, Domenico; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Skeie, Guri; Amiano, Pilar; Sánchez, María-José; Chirlaque, María-Dolores; Barricarte, Aurelio; Quirós, José Ramón; Buckland, Genevieve; van Gils, Carla H.; Peeters, Petra H.; Key, Timothy J.; Riboli, Elio; Gylling, Björn; Zeleniuch-Jacquotte, Anne; Gunter, Mark J.; Romieu, Isabelle; Chajès, Véronique (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-01)
      Epidemiological studies have reported inconsistent findings for the association between B vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers of folate and vitamin B12 and the risk of BC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Plasma concentrations of folate and vitamin B12 were determined in 2,491 BC cases individually ...
    • Circulating prolactin and in situ breast cancer risk in the European EPIC cohort: A case-control study 

      Tikk, Kaja; Sookthai, Disorn; Fortner, Renée T.; Johnson, Theron; Rinaldi, Sabina; Romieu, Isabelle; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Clavel-Chapelon, Françoise; Baglietto, Laura; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Mattiello, Amalia; Agudo, Antonio; Menéndez, Virginia; Sánchez, María-José; Amiano, Pilar; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Bueno-de-Mesquita, H. Bas; Monninkhof, Evelyn M.; Onland-Moret, N. Charlotte; Andresson, Anne; Sund, Malin; Weiderpass, Elisabete; Khaw, Kay-Tee; Key, Timothy J.; Travis, Ruth C.; Merritt, Melissa A.; Riboli, Elio; Dossus, Laure; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-31)
      Introduction: The relationship between circulating prolactin and invasive breast cancer has been investigated previously, but the association between prolactin levels and in situ breast cancer risk has received less attention.<p> <p>Methods: We analysed the relationship between pre-diagnostic prolactin levels and the risk of in situ breast cancer overall, and by menopausal status and use of ...
    • Circulating RANKL and RANKL/OPG and breast cancer risk by ER and PR subtype: Results from the EPIC cohort. 

      Sarink, Danja; Schock, Helena; Johnson, Theron; Overvad, Kim; Holm, Marianne; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; His, Mathilde; Kvaskoff, Marina; Boeing, Heiner; Lagiou, Pagona; Papatesta, Eleni-Maria; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; van Gils, Carla H.; Peeters, Petra H.; Weiderpass, Elisabete; Agudo, Antonio; Sánchez, María-José; Chirlaque, Maria-Dolores; Ardanaz, Eva; Amiano, Pilar; Khaw, Kay Tee; Travis, Ruth; Dossus, Laure; Gunter, Mark; Rinaldi, Sabina; Merritt, Melissa; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-31)
      Receptor activator of nuclear factor-kappa B (RANK)-RANK ligand (RANKL) signaling promotes mammary tumor development in experimental models. Circulating concentrations of soluble RANKL (sRANKL) may influence breast cancer risk via activation of RANK signaling; this may be modulated by osteoprotegerin (OPG), the decoy receptor for RANKL. sRANKL and breast cancer risk by hormone receptor subtype has ...
    • Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

      Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, María-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kühn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-04)
      Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited 385,747 participants with blood samples between 1992 and 2000. This analysis includes 497 case-control pairs ...
    • Development and validation of circulating CA125 prediction models in postmenopausal women 

      Sasamoto, Naoko; Babic, Ana; Rosner, Bernard A.; Fortner, Renée T.; Vitonis, Allison F; Yamamoto, Hidemi; Fichorova, Raina N.; Titus, Linda J.; Tjønneland, Anne; Hansen, Louise; Kvaskoff, Marina; Fournier, Agnès; Mancini, Francesca Romana; Boeing, Heiner; Trichopoulou, Antonia; Peppa, Eleni; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Mattiello, Amalia; Tumino, Rosario; Fiano, Valentina; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Gram, Inger Torhild; Quirós, José Ramón; Lujan-Barroso, Leila; Sánchez, María-José; Colorado-Yohar, Sandra; Barricarte, Aurelio; Amiano, Pilar; Idahl, Annika; Lundin, Eva; Sartor, Hanna; Khaw, Kay-Tee; Key, Timothy J.; Muller, David; Riboli, Elio; Gunter, Marc; Dossus, Laure; Trabert, Britton; Wentzensen, Nicolas; Kaaks, Rudolf; Cramer, Daniel W.; Tworoger, Shelley S.; Terry, Kathryn L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-26)
      <i>Background</i> - Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individuals. Personal characteristics that influence CA125 could be used to improve its performance as screening biomarker.<p><p> <i>Methods</i> - We developed and validated ...
    • Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort 

      Zamora-Ros, Raul; Barupal, Dinesh Kumar; Rothwell, Joseph A.; Jenab, Mazda; Fedirko, Veronika; Romieu, Isabelle; Aleksandrova, Krasimira; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Affret, Aurélie; His, Mathilde; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; Naska, Androniki; Kritikou, Maria; Saieva, Calogero; Agnoli, Claudia; Santucci de Magistris, Maria; Tumino, Rosario; Fasanelli, Francesca; Weiderpass, Elisabete; Skeie, Guri; Merino, Susana; Jakszyn, Paula; Sánchez, María-José; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Sonestedt, Emily; Ericson, Ulrika; Maria Nilsson, Lena; Bodén, Stina; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Perez-Cornago, Aurora; Wareham, Nicholas J.; Khaw, Kay-Thee; Freisling, Heinz; Cross, Amanda J.; Riboli, Elio; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-22)
      Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in colorectal cancer (CRC) development remains sparse and inconsistent. We evaluated the association between dietary intakes of total flavonoids and their subclasses and risk of ...
    • Exogenous hormone use and cutaneous melanoma risk in women: The European Prospective Investigation into Cancer and Nutrition 

      Cervenka, Iris; Al Rahmoun, Marie; Mahamat-Saleh, Yahya; Fournier, Agnès; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Caini, Saverio; Palli, Domenico; Ghiasvand, Reza; Veierød, Marit Bragelien; Botteri, Edoardo; Tjønneland, Anne; Olsen, Anja; Fortner, Renée T.; Kaaks, Rudolf; Schulze, Matthias B.; Panico, Salvatore; Trichopoulou, Antonia; Dessinioti, Clio; Niforou, Katerina; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Hendrik Bastiaan; Sandanger, Torkjel M; Colorado-Yohar, Sandra; Sánchez, María-José; Gil Majuelo, Leire; Lujan-Barroso, Leila; Ardanaz, Eva; Merino, Susana; Isaksson, Karolin; Butt, Salma; Ljuslinder, Ingrid; Jansson, Malin; Travis, Ruth C.; Khaw, Kay-Tee; Weiderpass, Elisabete; Dossus, Laure; Rinaldi, Sabina; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-10)
      Evidence suggests an influence of sex hormones on cutaneous melanoma risk, but epidemiologic findings are conflicting. We examined the associations between use of oral contraceptives (OCs) and menopausal hormone therapy (MHT) and melanoma risk in women participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is a prospective cohort study initiated in 1992 in 10 ...
    • Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: A nested case-control study 

      Fedirko, Veronika; Tran, Hao Quang; Gewirtz, Andrew T.; Stepien, Magdalena; Trichopoulou, Antonia; Aleksandrova, Krasimira; Olsen, Anja; Tjønneland, Anne; Overvad, Kim; Carbonnel, Franck; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Kühn, Tilman; Kaaks, Rudolf; Boeing, Heiner; Bamia, Christina; Lagiou, Pagona; Grioni, Sara; Panico, Salvatore; Palli, Domenico; Tumino, Rosario; Naccarati, Alessio; Peeters, Petra H.; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Castaño, José María Huerta; Barricarte, Aurelio; Sánchez, María-José; Dorronsoro, Miren; Quirós, José Ramón; Agudo, Antonio; Sjöberg, Klas; Ohlsson, Bodil; Hemmingsson, Oskar; Werner, Mårten; Bradbury, Kathryn E.; Khaw, Kay-Tee; Wareham, Nick; Tsilidis, Konstantinos K.; Aune, Dagfinn; Scalbert, Augustin; Romieu, Isabelle; Riboli, Elio; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-04)
      Background:<br>Leakage of bacterial products across the gut barrier may play a role in liver diseases which often precede the development of liver cancer. However, human studies, particularly from prospective settings, are lacking.<br>Methods:<br>We used a case-control study design nested within a large prospective cohort to assess the association between circulating levels of anti-lipopolysaccharide ...
    • Fiber intake modulates the association of alcohol intake with breast cancer 

      Romieu, Isabelle; Ferrari, Pietro; Chajès, Véronique; de Batlle, Jordi; Biessy, Carine; Scoccianti, Chiara; Dossus, Laure; Boutron, Marie Christine; Bastide, Nadia; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; Quirós, J Ramón; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano Etxezarreta, Pilar; Borgquist, Signe; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-06)
      Alcohol intake has been related to an increased risk of breast cancer (BC) while dietary fiber intake has been inversely associated to BC risk. A beneficial effect of fibers on ethanol carcinogenesis through their impact on estrogen levels is still controversial. We investigated the role of dietary fiber as a modifying factor of the association of alcohol and BC using data from the European Prospective ...
    • Flavonoid and lignan intake and pancreatic cancer risk in the European prospective investigation into cancer and nutrition cohort 

      Molina-Montes, Esther; Sánchez, María-José; Zamora-Ros, Raul; Bueno-de-Mesquita, H. Bas; Wark, Petra A.; Obon-Santacana, Mireia; Kühn, Tilman; Katzke, Verena; Travis, Ruth C.; Ye, Weimin; Sund, Malin; Naccarati, Alessio; Mattiello, Amalia; Krogh, Vittorio; Martorana, Caterina; Masala, Giovanna; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Quirós, José Ramón; Weiderpass, Elisabete; Åsli, Lene Angel; Skeie, Guri; Ericson, Ulrika; Sonestedt, Emily; Peeters, Petra H.; Romieu, Isabelle; Scalbert, Augustin; Overvad, Kim; Clemens, Matthias; Boeing, Heiner; Trichopoulou, Antonia; Peppa, Eleni; Vidalis, Pavlos; Khaw, Kay-Tee; Wareham, Nick; Olsen, Anja; Tjønneland, Anne; Boutroun-Rualt, Marie-Christine; Clavel-Chapelon, Françoise; Cross, Amanda J.; Lu, Yunxia; Riboli, Elio; Duell, Eric J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-10)
      Despite the potential cancer preventive effects of flavonoids and lignans, their ability to reduce pancreatic cancer risk has not been demonstrated in epidemiological studies. Our aim was to examine the association between dietary intakes of flavonoids and lignans and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. A total of 865 exocrine ...
    • Fruit and vegetable consumption in relation to hepatocellular carcinoma in a multi-centre, European cohort study 

      Bamia, Christina; Lagiou, Pagona; Jenab, Mazda; Aleksandrova, Krasimira; Fedirko, Veronika; Trichopoulos, Dimitrios; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Katzke, Verena A.; Kühn, Tilman; Boeing, Heiner; Nöthlings, Ute; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosaria; Naccarati, Allessio; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.M.; Weiderpass, Elisabete; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Chirlaque, María-Dolores; Sánchez, María-José; Ardanaz, Eva; Dorronsoro, Miren; Ericson, Ulrika; Nilsson, Lena Maria; Wennberg, Maria; Khaw, Kay-Tee; Wareham, Nicholas J.; Key, Timothy J.; Travis, Ruth C.; Ferrari, Pietro; Stepien, Magdalena; Duarte-Salles, Talita; Norat, Teresa; Murphy, Neil; Riboli, Eilo; Trichopoulou, Antonia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-05)
      Background: Vegetable and/or fruit intakes in association with hepatocellular carcinoma (HCC) risk have been investigated in case–control studies conducted in specific European countries and cohort studies conducted in Asia, with inconclusive results. No multi-centre European cohort has investigated the indicated associations. Methods: In 486 799 men/women from the European Prospective Investigation ...
    • Heterogeneity of colorectal cancer risk factors by anatomical subsite in 10 European countries: A multinational cohort study 

      Murphy, Neil; Ward, Heather A.; Jenab, Mazda; Rothwell, Joseph A.; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Kvaskoff, Marina; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Aleksandrova, Krasimira; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin Benjaminsen; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Dahm, Christina C.; Jakszyn, Paula; Sánchez, María-José; Gil, Leire; Huerta, José María; Barricarte, Aurelio; Quirós, José Ramón; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Trichopoulou, Antonia; La Vecchia, Carlo; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Fasanelli, Francesca; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.M.; Gylling, Björn; Myte, Robin; Jirström, Karin; Berntsson, Jonna; Xue, Xiaonan; Riboli, Elio; Cross, Amanda J.; Gunter, Mark J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-26)
      <i>Background & Aims</i> - Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly because most studies have been of insufficient size to identify heterogeneous associations with precision.<p><p> <i>Methods</i> - In the European Prospective Investigation ...
    • Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: Results from the EPIC cohort 

      Ose, Jennifer; Fortner, Renée T; Schock, Helena; Peeters, Petra H.; Onland-Moret, N. Charlotte; Bueno-de-Mesquita, H. Bas; Weiderpass, Elisabete; Gram, Inger Torhild; Overvad, Kim; Tjønneland, Anne; Dossus, Laure; Fournier, Agnes; Baglietto, Laura; Trichopoulou, Antonia; Benetou, Vassiliki; Trichopoulos, Dimitrios; Boeing, Heiner; Masala, Giovanna; Krogh, Vittorio; Matiello, Amalia; Tumino, Rosaria; Popovic, Maja; Obón-Santacana, Mireia; Larrañaga, Nerea; Ardanaz, Eva; Sánchez, María-José; Menéndez, Virginia; Chirlaque, María-Dolores; Travis, Ruth C.; Khaw, Kay-Tee; Brändstedt, Jenny; Idahl, Annika; Lundin, Eva; Rinaldi, Sabina; Kuhn, Elisabetta; Romieu, Isabelle; Gunter, Marc J.; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-04)
      Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics.<p> <p>Methods: We conducted a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics ...
    • Measured adiposity in relation to head and neck cancer risk in the European prospective investigation into cancer and nutrition. 

      Ward, Heather A.; Wark, Petra A.; Muller, David C.; Steffen, Annika; Johansson, Mattias; Norat, Teresa; Gunter, Marc J.; Overvad, Kim; Dahm, Christina C; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Mesrine, Sylvie; Brennan, Paul; Freisling, Heinz; Li, Kuanrong; Kaaks, Rudolf; Trichopoulou, Antonia; Lagiou, Pagona; Panico, Salavatore; Grioni, Sara; Tumino, Rosario; Vineis, Paolo; Palli, Domenico; Peeters, Petra H.M.; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Agudo, Antonio; Quirós, José Ramón; Larrañaga, Nerea; Ardanaz, Eva; Huerta, José María; Sánchez, María-José; Laurell, Göran; Johansson, Ingegerd; Westin, Ulla; Wallström, Peter; Bradbury, Kathryn E.; Wareham, Nicholas J.; Khaw, Kay-Tee; Pearson, Clare; Boeing, Heiner; Riboli, Elio (Journal article; Tidsskriftartikkel, 2017-06)
      <b>Background</b>: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer. However, most studies have used self-reported anthropometry which is prone to error.<br><b>Methods</b>: Among 363,094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 ...
    • Mediterranean diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort 

      Molina-Montes, Esther; Sánchez, María-José; Buckland, Genevieve; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Amiano, Pilar; Wark, Petra A.; Kühn, Tilman; Katzke, Verena; Huerta, José María; Ardanaz, Eva; Quirós, José Ramón; Affret, Aurelie; His, Mathilde; Boutron-Ruault, Marie-Christine; Peeters, Petra H.; Ye, Weimin; Sund, Malin; Boeing, Heiner; Iqbal, Khalid; Ohlsson, Bodil; Sonestedt, Emily; Tjønneland, Anne; Petersen, Kristina E.N.; Travis, Ruth C.; Skeie, Guri; Agnoli, Claudia; Panico, Salvatore; Palli, Domenico; Tumino, Rosario; Sacerdote, Carlotta; Freisling, Heinz; Huybrechts, Inge; Overvad, Kim; Trichopoulou, Antonia; Bamia, Christina; Vasilopoulou, Effie; Wareham, Nick; Khaw, Kay-Tee; Cross, Amanda J.; Ward, Heather A.; Riboli, Elio; Duell, Eric J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-07)
      Background: The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. <br>Methods: Over half a million ...
    • Menstrual factors, reproductive history, hormone use, and urothelial carcinoma risk: A prospective study in the EPIC cohort 

      Lujan-Barroso, Leila; Botteri, Edoardo; Caini, Saverio; Ljungberg, Börje; Roswall, Nina; Tjønneland, Anne; Bueno-De-Mesquita, Bas; Gram, Inger Torhild; Tumino, Rosario; Kiemeney, Lambertus A.; Liedberg, Fredrik; Stocks, Tanja; Gunter, Marc; Murphy, Neil; Cervenka, Iris; Fournier, Agnès; Kvaskoff, Marina; Häggström, Christel; Overvad, Kim; Lund, Eiliv; Waaseth, Marit; Fortner, Renée T.; Kühn, Tilman; Menéndez, Virginia; Sánchez, María-José; Santiuste, Carmen; Perez-Cornago, Aurora; Zamora-Ros, Raul; Cross, Amanda J.; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Krogh, Vittorio; Sciannameo, Veronica; Mattiello, Amalia; Panico, Salvatore; van Gils, Carla H.; Onland-Moret, N. Charlotte; Barricarte, Aurelio; Amiano, Pilar; Khaw, Kay-Tee; Boeing, Heiner; Weiderpass, Elisabete; Duell, Eric J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-28)
      <p>Background: Urothelial carcinoma is the predominant (95%) bladder cancer subtype in industrialized nations. Animal and epidemiologic human studies suggest that hormonal factors may influence urothelial carcinoma risk. <p>Methods: We used an analytic cohort of 333,919 women from the European Prospective Investigation into Cancer and Nutrition Cohort. Associations between hormonal factors and ...